The Coro1B Polyclonal Antibody (CAB14593) is a valuable tool for researchers studying Coro1B, a protein involved in actin cytoskeleton organization and cell migration. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.Coro1B, also known as Coronin 1B, plays a crucial role in regulating the dynamics of the actin cytoskeleton, which is essential for cell motility and immune cell function. Dysregulation of Coro1B has been linked to various diseases, including cancer and autoimmune disorders, making it a promising target for therapeutic interventions.
By using the Coro1B Polyclonal Antibody, researchers can detect and analyze Coro1B protein levels in different cell types, providing valuable insights into its function and potential role in disease pathogenesis. This antibody is a valuable tool for studies in cell biology, immunology, and cancer research, paving the way for new discoveries and potential therapeutic strategies.
Product Name:
CORO1B Rabbit Polyclonal Antibody
SKU:
CAB14593
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-489 of human CORO1B (NP_065174.1).
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).
Purification Method:
Affinity purification
Gene ID:
57175
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat kidney, using CORO1B Rabbit pAb (CAB14593) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
