The Coronin-1A Polyclonal Antibody (CAB9300) is a research tool designed for studying Coronin-1A, a protein involved in various cellular processes such as actin cytoskeleton organization and cell migration. This antibody, derived from rabbit serum, is highly specific for Coronin-1A in human samples and is validated for use in Western blot applications.Coronin-1A is a key player in the regulation of cell motility and immune cell function, making it a promising target for research in immunology, cancer biology, and cell biology. By detecting and analyzing Coronin-1A levels in different cell types, researchers can gain insights into its roles in cellular dynamics and disease pathogenesis.
The importance of Coronin-1A in cellular processes and disease mechanisms underscores the significance of this antibody for studies aiming to uncover the molecular mechanisms underlying various pathological conditions. Its specificity and reliability make it a valuable tool for scientists investigating the functions of Coronin-1A and its implications in health and disease.
Product Name:
CORO1A Rabbit Polyclonal Antibody
SKU:
CAB9300
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-461 of human CORO1A (NP_001180262.1).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
Purification Method:
Affinity purification
Gene ID:
11151
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CORO1A Rabbit pAb (CAB9300) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
