The Corin Polyclonal Antibody (CAB10404) is a valuable tool for researchers studying the role of the corin protein in various physiological processes. Corin is a transmembrane serine protease that plays a key role in the regulation of blood pressure and cardiac function. This antibody, generated in rabbits, is highly specific to human corin and has been validated for use in Western blot applications.By targeting the corin protein, researchers can investigate its involvement in cardiovascular diseases, such as hypertension and heart failure.
Understanding the mechanisms by which corin functions can provide valuable insights into disease pathology and potential therapeutic targets.With its high reactivity and specificity, the Corin Polyclonal Antibody is an essential tool for scientists looking to delve deeper into the role of corin in cardiovascular health and disease. Its application in research can lead to a better understanding of the molecular mechanisms underlying cardiovascular disorders, ultimately paving the way for the development of targeted therapies.
Product Name:
CORIN Rabbit Polyclonal Antibody
SKU:
CAB10404
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CORIN (NP_006578.2).
Cell membrane, Secreted, Single-pass type II membrane protein, Single-pass type II membrane protein.
Calculated MW:
116kDa
Observed MW:
116kDa
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10699
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CORIN antibody (CAB10404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
