| UniProt Protein Function: | COQ4: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. Belongs to the COQ4 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: MitochondrialChromosomal Location of Human Ortholog: 9q34.11Cellular Component: mitochondrionBiological Process: ubiquinone biosynthetic processDisease: Coenzyme Q10 Deficiency, Primary, 7 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the coenzyme Q biosynthesis pathway. Coenzyme Q, an essential component of the electron transport chain, shuttles electrons between complexes I or II to complex III of the mitochondrial transport chain. This protein appears to play a structural role in stabilizing a complex that contains most of the coenzyme Q biosynthesis enzymes. Mutations in this gene are associated with mitochondrial disorders linked to coenzyme Q deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
| UniProt Code: | Q9Y3A0 |
| NCBI GenInfo Identifier: | 40225458 |
| NCBI Gene ID: | 51117 |
| NCBI Accession: | BC011895 |
| UniProt Secondary Accession: | Q9Y3A0,Q5T4B8, Q96EW4, A8WBK8, B2R958 |
| UniProt Related Accession: | Q9Y3A0 |
| Molecular Weight: | 27,043 Da |
| NCBI Full Name: | Homo sapiens coenzyme Q4 homolog (S. cerevisiae), mRNA |
| NCBI Synonym Full Names: | coenzyme Q4 |
| NCBI Official Symbol: | COQ4Â Â |
| NCBI Official Synonym Symbols: | CGI-92; COQ10D7Â Â |
| NCBI Protein Information: | ubiquinone biosynthesis protein COQ4 homolog, mitochondrial |
| UniProt Protein Name: | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial |
| UniProt Synonym Protein Names: | Coenzyme Q biosynthesis protein 4 homolog |
| Protein Family: | Ubiquinone biosynthesis protein |
| UniProt Gene Name: | COQ4Â Â |
| UniProt Entry Name: | COQ4_HUMAN |
