The CoQ10B Polyclonal Antibody (CAB15193) is specifically designed for research involving Coenzyme Q10B, a vital molecule involved in cellular energy production and antioxidant defense. This antibody, derived from rabbit immunoglobulins, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CoQ10B protein, researchers can accurately detect and analyze its presence in various cell types, making it an essential tool for studies in mitochondrial function, aging, and oxidative stress.Coenzyme Q10B, also known as ubiquinone, plays a crucial role in the electron transport chain and ATP production, making it essential for cellular energy metabolism.
Its antioxidant properties also protect cells from oxidative damage, highlighting its importance in maintaining cell health and function. Research on CoQ10B is particularly relevant in studying aging-related diseases, neurodegenerative disorders, and metabolic syndromes, as its deficiency has been linked to these conditions. By understanding the functions and regulatory mechanisms of CoQ10B, researchers can uncover potential therapeutic targets for treating various diseases associated with mitochondrial dysfunction and oxidative stress.
Product Name:
COQ10B Rabbit Polyclonal Antibody
SKU:
CAB15193
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 38-150 of human COQ10B (NP_079423.1).
Sequence:
ASCG ILMS RTLP LHTS ILPK EICA RTFF KITA PLIN KRKE YSER RILG YSMQ EMYD VVSG VEDY KHFV PWCK KSDV ISKR SGYC KTRL EIGF PPVL ERYT SVVT LVKP HLVK A
Predicted to enable ubiquinone binding activity. Predicted to be involved in cellular respiration and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
80219
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using COQ10B Rabbit pAb (CAB15193) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
