COPS8 Rabbit Polyclonal Antibody (CAB12745)
- SKU:
- CAB12745
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | COPS8 Rabbit Polyclonal Antibody |
SKU: | CAB12745 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human COPS8 (NP_006701.1). |
Sequence: | MPVA VMAE SAFS FKKL LDQC ENQE LEAP GGIA TPPV YGQL LALY LLHN DMNN ARYL WKRI PPAI KSAN SELG GIWS VGQR IWQR DFPG IYTT INAH QWSE TVQP IMEA LRDA TRRR AFAL VSQA YTSI IADD FAAF VGLP VEEA VKGI LEQG WQAD STTR MVLP RKPV AGAL DVSF NKFI PLSE PAPV PPIP NEQQ LARL TDYV AFLE N |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | COP9; CSN8; SGN8; COPS8 |
Positive Sample: | U-87MG,A375,HeLa,HepG2,Mouse brain,Mouse heart,Mouse liver,Mouse testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 10920 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |