The COPS7A Polyclonal Antibody (CAB8212) is a valuable tool for researchers studying COPS7A, a key protein involved in cellular functions such as protein ubiquitination and DNA repair. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications.COPS7A, a subunit of the COP9 signalosome complex, plays a crucial role in regulating the stability and activity of various proteins involved in cell growth and proliferation. Dysregulation of COPS7A has been implicated in the development of cancer and other diseases, making it a promising target for therapeutic intervention.
By targeting the COPS7A protein, researchers can gain insights into its functions and molecular interactions in different cell types, paving the way for advancements in cancer research and drug discovery. This antibody will enable precise detection and analysis of COPS7A, contributing to a deeper understanding of its role in cellular processes and disease pathogenesis.
Product Name:
COPS7A Rabbit Polyclonal Antibody
SKU:
CAB8212
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human COPS7A (NP_057403.1).
This gene encodes a component of the COP9 signalosome, an evolutionarily conserved multi-subunit protease that regulates the activity of the ubiquitin conjugation pathway. Alternatively spliced transcript variants that encode the same protein have been described.
Purification Method:
Affinity purification
Gene ID:
50813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using COPS7A antibody (CAB8212) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
