COPS6 Rabbit Polyclonal Antibody (CAB7072)
- SKU:
- CAB7072
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | COPS6 Rabbit Polyclonal Antibody |
SKU: | CAB7072 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6 (NP_006824.2). |
Sequence: | MRSQ EGRP VQVI GALI GKQE GRNI EVMN SFEL LSHT VEEK IIID KEYY YTKE EQFK QVFK ELEF LGWY TTGG PPDP SDIH VHKQ VCEI IESP LFLK LNPM TKHT DLPV SVFE SVID IING EATM LFAE LTYT LATE EAER IGVD HVAR MTAT GSGE NSTV AEHL IAQH SAIK MLHS RVKL ILEY VKAS EAGE VPFN HEIL REAY ALCH CLPV LSTD KFKT DFYD QCND VGLM AYLG TITK TCNT MNQF VNKF NVLY DRQG IGRR MRGL FF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:100 |
Synonyms: | CSN6; MOV34-34KD; COPS6 |
Positive Sample: | MCF7,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Purification Method: | Affinity purification |
Gene ID: | 10980 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |