The anti-COPS3 Antibody (CAB19584) is a high-quality polyclonal antibody designed for research involving COPS3, a key protein involved in the regulation of the COP9 signalosome complex. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studies in molecular biology and signal transduction pathways.COPS3, also known as COP9 signalosome subunit 3, plays a crucial role in the ubiquitin-proteasome system, regulating protein degradation and influencing various cellular processes. Its involvement in protein turnover and cell cycle control highlights its importance in cell function and homeostasis.
The anti-COPS3 Antibody enables the detection and analysis of COPS3 protein levels in different cell types, offering valuable insights into its function and potential implications in disease states.Research into COPS3 is essential for understanding its impact on cellular processes and potential therapeutic targets in diseases such as cancer, neurodegenerative disorders, and metabolic diseases. The anti-COPS3 Antibody provides a reliable tool for investigating COPS3 function and its role in various biological pathways, advancing our knowledge of this critical protein's contributions to health and disease.
Product Name:
COPS3 Rabbit Monoclonal Antibody
SKU:
CAB19584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-423 of human COPS3 (Q9UNS2).
Cytoplasm, Cytosol, Nucleoplasm, Nucleus, Perinuclear region of cytoplasm
Calculated MW:
48kDa
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8533
Clone Number:
ARC2182
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using COPS3 Rabbit mAb (CAB19584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
