The COPB1 Polyclonal Antibody (CAB10485) is a valuable tool for researchers studying COPB1, a protein involved in intracellular transport and Golgi function. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the COPB1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and molecular biology.COPB1 is a key component of the COPI coat complex, which is essential for retrograde transport between Golgi compartments and the endoplasmic reticulum.
Understanding the function of COPB1 is crucial for elucidating the mechanisms of intracellular transport and protein trafficking. Research into COPB1 may have implications for various diseases, including neurodegenerative disorders and cancer, where disruptions in intracellular transport can contribute to disease progression.Overall, the COPB1 Polyclonal Antibody is a valuable tool for researchers investigating the role of COPB1 in cellular processes and disease pathways. Its specificity and reliability make it an essential component of any study involving COPB1 and intracellular transport mechanisms.
Product Name:
COPB1 Rabbit Polyclonal Antibody
SKU:
CAB10485
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human COPB1 (NP_057535.1).
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
1315
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using COPB1 Rabbit pAb (CAB10485) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
