The COP1 Polyclonal Antibody is a vital tool for researchers studying the COP1 protein, a key regulator of cell growth and division. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting COP1 in human samples. Validated for use in Western blotting, it allows for the precise identification and analysis of COP1 expression in various cell types.COP1, known for its role in controlling cell proliferation and apoptosis, is a crucial factor in cancer development and progression.
By targeting COP1, researchers can gain valuable insights into the mechanisms underlying tumorigenesis and potentially identify new therapeutic targets for cancer treatment. This antibody is an essential component for studies investigating the function of COP1 in cancer biology and may lead to the development of novel anti-cancer therapies.
Product Name:
COP1 Polyclonal Antibody
SKU:
CAB22106
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 582-731 of human COP1 (NP_071902.2).
Enables ubiquitin protein ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Part of Cul4A-RING E3 ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
64326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of 293T, using COP1 Rabbit pAb (CAB22106) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
