The Contactin-4 Polyclonal Antibody (CAB10339) is a valuable tool for research involving Contactin-4, a cell adhesion molecule that plays a crucial role in the development and maintenance of the nervous system. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.Contactin-4 is known to be involved in neuronal cell adhesion, axon guidance, and synapse formation, making it a key player in neurodevelopmental processes. Research suggests that dysregulation of Contactin-4 may be implicated in neurological disorders such as autism spectrum disorders and schizophrenia.
By using the Contactin-4 Polyclonal Antibody, researchers can effectively detect and analyze Contactin-4 protein expression in various cell types, allowing for a better understanding of its function and potential role in disease pathology. This antibody is a valuable tool for studies in neuroscience, neurodevelopment, and neurodegenerative diseases, providing insights that could lead to the development of novel therapeutic approaches.
Product Name:
CNTN4 Rabbit Polyclonal Antibody
SKU:
CAB10339
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 448-697 of human CNTN4 (NP_001193885.1).
This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
152330
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CNTN4 antibody (CAB10339) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
