The Connexin-43 Monoclonal Antibody (CAB23120) is a valuable tool for researchers studying connexin-43, a crucial protein involved in cell communication and intercellular signaling. This antibody, produced through monoclonal antibody technology, is highly specific to connexin-43 and is suitable for use in a variety of research applications, including immunofluorescence and immunohistochemistry.Connexin-43 is a key player in maintaining tissue homeostasis and regulating cell growth and proliferation. Dysregulation of connexin-43 has been implicated in various diseases, including cardiovascular disorders, neurodegenerative diseases, and cancer.
By targeting connexin-43 with this monoclonal antibody, researchers can gain a better understanding of its function and potential involvement in disease pathogenesis.With its high specificity and sensitivity, the Connexin-43 Monoclonal Antibody (CAB23120) is a valuable asset for researchers looking to unravel the complexities of cell-to-cell communication and its impact on various physiological and pathological processes. Its use in studies involving connexin-43 can lead to novel insights and potential therapeutic targets for a range of diseases.
Product Name:
Connexin 43 Monoclonal Antibody
SKU:
CAB23120
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-382 of human Connexin 43 (NP_000156.1).
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
Purification Method:
Affinity purification
Gene ID:
2697
Clone Number:
ARC58819
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Connexin 43 antibody (CAB23120) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
