The COMTD1 Polyclonal Antibody (CAB14300) is an essential tool for researchers studying COMTD1, a key enzyme involved in the biosynthesis of 3-methoxytyramine. This antibody, generated in rabbits, exhibits exceptional reactivity with human samples and has been validated for use in Western blot applications. By binding to the COMTD1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for investigations in neurobiology and drug development. COMTD1 plays a crucial role in the metabolism of catecholamines, neurotransmitters that regulate mood, stress response, and cognitive function.
Dysregulation of COMTD1 activity has been linked to various neurological disorders, including Parkinson's disease and schizophrenia. By elucidating the function of COMTD1, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify novel therapeutic targets. Overall, the COMTD1 Polyclonal Antibody is a valuable tool for advancing our understanding of catecholamine metabolism and its implications for neurological health. Its exceptional specificity and sensitivity make it an ideal choice for researchers seeking to uncover the role of COMTD1 in health and disease.
Product Name:
COMTD1 Rabbit Polyclonal Antibody
SKU:
CAB14300
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-262 of human COMTD1 (NP_653190.2).
Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
118881
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using COMTD1 Rabbit pAb (CAB14300) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
