The Complement Factor H Polyclonal Antibody (CAB2166) is a powerful tool for researchers studying the complement system, a key component of the immune response. Complement Factor H is a regulatory protein that helps to control the activation of the complement system, preventing excessive inflammation and tissue damage.Raised in rabbits, this antibody is highly specific to human Complement Factor H and has been validated for use in a variety of applications, including Western blotting and immunohistochemistry.
By targeting Complement Factor H, researchers can investigate its role in various diseases, including autoimmune disorders, inflammatory conditions, and age-related macular degeneration.With its high reactivity and specificity, the Complement Factor H Polyclonal Antibody (CAB2166) is an essential tool for any researcher looking to delve deeper into the intricate workings of the complement system and its impact on human health.
Product Name:
CFH Rabbit Polyclonal Antibody
SKU:
CAB2166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-323 of human Complement factor H (NP_000177.2).
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
3075
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Complement factor H Rabbit pAb (CAB2166) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
