Complement C3 Rabbit Monoclonal Antibody (CAB11196)
- SKU:
- CAB11196
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Complement C3 Rabbit Monoclonal Antibody |
SKU: | CAB11196 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human Complement Complement C3 (P01024). |
Sequence: | GRLK GPLL NKFL TTAK DKNR WEDP GKQL YNVE ATSY ALLA LLQL KDFD FVPP VVRW LNEQ RYYG GGYG STQA TFMV FQAL AQYQ KDAP DHQE LNLD VSLQ L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; Complement C3 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 187kDa |
Observed MW: | 115kDa/187kDa |
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Purification Method: | Affinity purification |
Gene ID: | 718 |
Clone Number: | ARC0541 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |