COMP Rabbit Polyclonal Antibody (CAB5812)
- SKU:
- CAB5812
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | COMP Rabbit Polyclonal Antibody |
SKU: | CAB5812 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_000086.2). |
Sequence: | GQGQ SPLG SDLG PQML RELQ ETNA ALQD VREL LRQQ VREI TFLK NTVM ECDA CGMQ QSVR TGLP SVRP LLHC APGF CFPG VACI QTES GARC GPCP AGFT GNGS HCTD VNEC NAHP CFPR VRCI NTSP GFRC EACP PGYS G |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | MED; CTS2; EDM1; EPD1; TSP5; PSACH; THBS5; TSP-5; COMP |
Positive Sample: | SKOV3,U2OS,Mouse skeletal muscle,Mouse bone,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 83kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Purification Method: | Affinity purification |
Gene ID: | 1311 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |