The COMMD9 Polyclonal Antibody (PAC041758) is a valuable tool for researchers studying the COMMD9 protein, which plays a crucial role in cellular processes related to inflammation, immune response, and cancer development. This antibody, specifically developed for use in Western blot applications, is raised in rabbits and exhibits high reactivity with human samples.COMMD9 is a regulatory protein involved in various cellular pathways, including the NF-κB signaling pathway, which is essential for immune responses and inflammation. Studies have shown that dysregulation of COMMD9 expression is associated with cancer progression and inflammatory diseases, making it a promising target for therapeutic interventions.
By detecting and analyzing the COMMD9 protein in different cell types, researchers can gain valuable insights into its function and potential as a biomarker for disease prognosis and treatment. The COMMD9 Polyclonal Antibody is a reliable tool for exploring the role of COMMD9 in health and disease, making it a valuable asset in immunology and cancer research.
Antibody Name:
COMMD9 Antibody (PACO41758)
Antibody SKU:
PACO41758
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human COMM domain-containing protein 9 protein (1-198AA)
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO41758 at dilution of 1:100.
Background:
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits.
Synonyms:
COMM domain-containing protein 9, COMMD9
UniProt Protein Function:
COMMD9: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11p13Molecular Function: protein binding
