The COMM domain-containing protein 4 (COMMD4) Antibody (PAC031884) is an essential tool for researchers studying the role of COMMD4 in cellular processes. COMMD4, a key protein involved in the regulation of various biological pathways, is known to play a crucial role in copper homeostasis, NF-kappaB signaling, and protein transport. The polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting COMMD4 in human samples, making it an ideal choice for Western blot applications.COMMD4's involvement in multiple cellular functions makes it a valuable target for investigation in a variety of research areas, including cell biology, molecular biology, and biochemistry.
By utilizing the COMMD4 Antibody, researchers can gain insights into the mechanisms underlying COMMD4-mediated processes and potentially uncover novel therapeutic targets for diseases related to dysregulated cellular pathways.Overall, the COMMD4 Antibody is a reliable tool for researchers seeking to explore the functional roles of COMMD4 and its implications in various biological contexts. Its high specificity, sensitivity, and versatility make it a valuable asset for studies focused on unraveling the complex functions of this essential protein.
Antibody Name:
COMMD4 Antibody (PACO31884)
Antibody SKU:
PACO31884
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human COMM domain-containing protein 4 protein (1-195AA)
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO31884 at dilution of 1:100.
Background:
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B.
Synonyms:
COMM domain-containing protein 4, COMMD4
UniProt Protein Function:
COMMD4: Down-regulates activation of NF-kappa-B. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 15q24.2Cellular Component: cytoplasmMolecular Function: protein binding
