The COMM domain-containing protein 10 (COMMD10) Polyclonal Antibody (PAC046770) is a valuable tool for researchers studying the function of COMMD10, a protein involved in various cellular processes, including copper homeostasis and NF-κB signaling. This rabbit polyclonal antibody is highly specific for human COMMD10 and has been validated for use in Western blot applications.COMMD10 is known to interact with a variety of proteins and play a role in regulating cellular pathways that are important for cell growth and survival.
Dysfunction of COMMD10 has been implicated in several diseases, making it a promising target for further investigation in the fields of molecular biology and medicine.Researchers interested in understanding the molecular mechanisms underlying COMMD10 function and its potential implications in disease pathogenesis will find this antibody to be a valuable tool for their experiments. Its specificity and reliability make it a trusted reagent for studies aimed at elucidating the role of COMMD10 in health and disease.
Antibody Name:
COMMD10 Antibody (PACO46770)
Antibody SKU:
PACO46770
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human COMM domain-containing protein 10 protein (84-172AA)
Immunofluorescent analysis of HepG2 cells using PACO46770 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.
Synonyms:
COMM domain-containing protein 10, COMMD10
UniProt Protein Function:
COMMD10: Interacts (via COMM domain) with COMMD1 (via COMM domain).Protein type: Unknown functionChromosomal Location of Human Ortholog: 5q23.1Molecular Function: protein binding
