The Collectin-11 Polyclonal Antibody (CAB4955) is a valuable tool for researchers studying Collectin-11, a soluble pattern recognition molecule involved in innate immunity. This antibody, produced using rabbit immunization, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Collectin-11 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a versatile option for studies in immunology and infectious diseases.
Collectin-11 plays a key role in host defense mechanisms by recognizing and binding to pathogens, leading to their clearance from the body. Its involvement in innate immune responses makes it a promising target for research on infectious diseases and immune system function. By investigating the functions and regulation of Collectin-11, researchers can gain insights into its role in antimicrobial defense and potential therapeutic applications in combating infections.
Product Name:
COLEC11 Rabbit Polyclonal Antibody
SKU:
CAB4955
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-271 of human COLEC11 (NP_076932.1).
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
78989
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using COLEC11 Rabbit pAb (CAB4955) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
