The Collectin-12 Polyclonal Antibody (CAB10422) is an essential tool for researchers studying the role of Collectin-12, a key player in the immune response system. This antibody, produced in rabbits, is highly specific for human samples and has been validated for Western blot applications. By binding to the Collectin-12 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in immunology and cancer research.Collectin-12, also referred to as CL-P1, is a member of the collectin family of proteins that are involved in innate immunity and inflammation. Known for its ability to bind to pathogens and activate the immune response, Collectin-12 is a crucial component in the body's defense against infection and disease.
Research into the function of Collectin-12 is vital for understanding its role in various health conditions, including infectious diseases, autoimmune disorders, and inflammatory conditions.Overall, the Collectin-12 Polyclonal Antibody is a powerful tool for researchers looking to explore the function and implications of Collectin-12 in the immune system and its potential as a therapeutic target in various disease settings. With its high specificity and reliability, this antibody is a valuable asset for advancing our understanding of immune response mechanisms and developing new treatment strategies.
Product Name:
COLEC12 Rabbit Polyclonal Antibody
SKU:
CAB10422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_569057.1).
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Purification Method:
Affinity purification
Gene ID:
81035
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using COLEC12 antibody (CAB10422) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
