The COL9A3 Polyclonal Antibody (CAB9798) is a valuable tool for researchers studying COL9A3, a gene associated with collagen production and extracellular matrix formation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blotting. By binding to the COL9A3 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in connective tissue disorders, musculoskeletal diseases, and cartilage biology.COL9A3 is a critical component of type IX collagen, which plays a crucial role in maintaining the structural integrity of tissues such as cartilage and intervertebral discs.
Dysregulation of COL9A3 expression has been linked to conditions like osteoarthritis, intervertebral disc degeneration, and other connective tissue disorders. Understanding the function and regulation of COL9A3 is essential for developing therapeutic interventions that target these diseases at the molecular level.Overall, the COL9A3 Polyclonal Antibody (CAB9798) is a reliable tool for researchers looking to delve into the intricate mechanisms of collagen biology and explore the role of COL9A3 in health and disease. Its high specificity and sensitivity make it an invaluable resource for advancing our understanding of connective tissue disorders and developing targeted therapies for these conditions.
Product Name:
COL9A3 Rabbit Polyclonal Antibody
SKU:
CAB9798
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 445-684 of human COL9A3 (NP_001844.3).
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3.
Purification Method:
Affinity purification
Gene ID:
1299
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Mouse heart using COL9A3 Rabbit pAb (CAB9798) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
