The COL9A2 Polyclonal Antibody (CAB17461) is a powerful tool for researchers studying COL9A2, a gene encoding a type of collagen protein found in the extracellular matrix of cartilage. This antibody, developed in rabbits, exhibits high specificity and sensitivity for human samples, making it an excellent choice for applications such as immunohistochemistry and ELISA.COL9A2 is vital for the structural integrity of cartilage and plays a crucial role in maintaining joint health. Dysregulation of this gene has been linked to various musculoskeletal disorders, including osteoarthritis and intervertebral disc degeneration. By targeting COL9A2, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
The COL9A2 Polyclonal Antibody is a reliable tool for investigating the role of COL9A2 in cartilage biology and disease pathogenesis. Its versatility and high performance make it a valuable asset for studies focused on understanding the molecular mechanisms governing cartilage development and maintenance. Whether exploring basic science questions or developing new therapies, this antibody offers researchers a precise and efficient means of investigating COL9A2 function.
Product Name:
COL9A2 Rabbit Polyclonal Antibody
SKU:
CAB17461
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-689 of human COL9A2 (NP_001843.1).
endoplasmic reticulum lumen, extracellular region, extracellular space
Calculated MW:
65kDa
Observed MW:
65kDa
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.
Purification Method:
Affinity purification
Gene ID:
1298
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver, using COL9A2 Rabbit pAb (CAB17461) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
