COL9A1 Rabbit Polyclonal Antibody (CAB6563)
- SKU:
- CAB6563
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | COL9A1 Rabbit Polyclonal Antibody |
SKU: | CAB6563 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human COL9A1 (NP_001842.3). |
Sequence: | WASA AVKR RPRF PVNS NSNG GNEL CPKI RIGQ DDLP GFDL ISQF QVDK AASR RAIQ RVVG SATL QVAY KLGN NVDF RIPT RNLY PSGL PEEY SFLT TFRM TGST LKKN WNIW QIQD SSGK EQVG IKIN GQTQ SVVF SYKG LDGS LQTA AFSN LSSL FDSQ WHKI MIGV ERSS ATLF VDCN RIES LPIK PRGP IDID GFAV LGKL ADNP QVSV PFEL QWML IHCD PLRP RRET CHEL PARI TPSQ TTDE RGP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MED; EDM6; STL4; DJ149L1.1.2; COL9A1 |
Positive Sample: | Rat lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 92kDa |
Observed MW: | 92kDa |
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1297 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |