Collagen VI/COL6A1 Rabbit Polyclonal Antibody (CAB9236)
- SKU:
- CAB9236
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Collagen VI/COL6A1 Rabbit Polyclonal Antibody |
SKU: | CAB9236 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-250 of human Collagen VI/Collagen VI/COL6A1 (NP_001839.2). |
Sequence: | AQDE PETP RAVA FQDC PVDL FFVL DTSE SVAL RLKP YGAL VDKV KSFT KRFI DNLR DRYY RCDR NLVW NAGA LHYS DEVE IIQG LTRM PGGR DALK SSVD AVKY FGKG TYTD CAIK KGLE QLLV GGSH LKEN KYLI VVTD GHPL EGYK EPCG GLED AVNE AKHL GVKV FSVA ITPD HLEP RLSI IATD HTYR RNFT AADW GQSR DAEE AISQ TIDT IVDM IKNN VEQV CCSF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OPLL; BTHLM1; UCHMD1; Collagen VI/COL6A1 |
Positive Sample: | SKOV3,HepG2,HT-1080,Mouse heart,Mouse lung,Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 109kDa |
Observed MW: | 108kDa |
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Purification Method: | Affinity purification |
Gene ID: | 1291 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |