Collagen III alpha 1/COL3A1 Rabbit Polyclonal Antibody (CAB3795)
The COL3A1 Polyclonal Antibody (CAB3795) is specifically designed for research involving COL3A1, a protein that is a major component of the extracellular matrix in collagen-rich tissues such as skin, lung, and blood vessels. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blotting and immunohistochemistry.COL3A1 is involved in maintaining the structural integrity and strength of tissues, making it a key player in processes such as wound healing and tissue repair. Its dysregulation has been linked to various conditions such as connective tissue disorders, vascular diseases, and fibrotic disorders.
Therefore, the COL3A1 Polyclonal Antibody is a valuable tool for studying the role of COL3A1 in such diseases and exploring potential therapeutic targets.By enabling the detection and analysis of COL3A1 in different cell types and tissues, this antibody is essential for researchers in the fields of collagen biology, tissue engineering, and regenerative medicine. Its high specificity and sensitivity make it an ideal choice for studying the function and regulation of COL3A1 in both normal physiology and disease pathology.
Product Name:
Collagen III alpha 1/COL3A1 Rabbit Polyclonal Antibody
SKU:
CAB3795
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1201-1301 of human Collagen III alpha 1/COL3A1 (NP_000081.2).
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome type IV, and with aortic and arterial aneurysms.
Purification Method:
Affinity purification
Gene ID:
1281
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells using Collagen III alpha 1/COL3A1 Rabbit pAb(CAB3795) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
