The COL28A1 Polyclonal Antibody (PACO07271) is a valuable tool for research involving COL28A1, a type XXVIII collagen protein involved in various biological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting and immunohistochemistry applications. By binding specifically to the COL28A1 protein, this antibody enables researchers to detect and analyze the expression of COL28A1 in different cell types, making it ideal for studies in areas such as tissue development, extracellular matrix organization, and fibrosis.COL28A1 is a collagen protein that has been implicated in tissue development and maintenance, particularly in the cornea, where it contributes to maintaining transparency and structural integrity.
Dysregulation of COL28A1 expression has been associated with several diseases, including corneal dystrophies and other connective tissue disorders. Therefore, investigating the role of COL28A1 in these conditions is essential for developing targeted therapies and diagnostic tools.In summary, the COL28A1 Polyclonal Antibody (PACO07271) is a valuable asset for researchers studying COL28A1 and its implications in various biological processes and disease states. Its high specificity and reactivity make it a reliable tool for advancing our understanding of the role of COL28A1 in health and disease.
Antibody Name:
COL28A1 Antibody (PACO07271)
Antibody SKU:
PACO07271
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000-1:20000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from Collagen α-1(XXVIII)Polyclonal Antibody at AA range: 111-160
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of 3T3 HEPG2 cells using Collagen alpha-1(XXVIII)Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000.
Synonyms:
Collagen α-1(XXVIII) chain
UniProt Protein Function:
May act as a cell-binding protein.
NCBI Summary:
COL28A1 belongs to a class of collagens containing von Willebrand factor (VWF; MIM 613160) type A (VWFA) domains (Veit et al., 2006 [PubMed 16330543]).[supplied by OMIM, Nov 2010]