The COL23A1 Polyclonal Antibody (PACO05701) is a valuable tool for researchers studying COL23A1, a type II transmembrane collagen protein with potential roles in extracellular matrix organization and cell adhesion. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in various applications, including Western blotting.COL23A1 is a collagen molecule that has been implicated in skin biology and wound healing processes. Its expression has been detected in various tissues, suggesting its involvement in tissue repair and regeneration.
By targeting COL23A1 with this antibody, researchers can gain insights into its function and explore its potential as a therapeutic target in skin-related diseases and conditions.Further investigation into the regulatory mechanisms of COL23A1 could provide valuable information for advancing the fields of dermatology, wound healing, and tissue engineering. This antibody offers a reliable tool for studying COL23A1 expression and function, opening up opportunities for new discoveries in these areas of research.
Antibody Name:
COL23A1 Antibody (PACO05701)
Antibody SKU:
PACO05701
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:10000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the C-terminal region of human COL23A1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
COL23A1; Collagen α-1(XXIII) chain
UniProt Protein Function:
COL23A1: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 5q35.3Cellular Component: collagen; endoplasmic reticulum lumen; integral to membrane; plasma membraneBiological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis
UniProt Protein Details:
NCBI Summary:
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]