The COL19A1 Polyclonal Antibody (PACO3453) is a valuable tool for researchers studying COL19A1, a collagen type XIX protein involved in various biological processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By specifically targeting the COL19A1 protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal choice for studies in developmental biology, tissue remodeling, and extracellular matrix regulation.COL19A1 is an integral component of extracellular matrix structures, playing a crucial role in tissue development and maintenance. Its involvement in cellular adhesion and matrix organization makes it a key player in processes like wound healing, angiogenesis, and tissue regeneration.
Research on COL19A1 is particularly relevant in understanding diseases related to connective tissue disorders, musculoskeletal conditions, and fibrotic diseases, providing valuable insights for therapeutic interventions targeting these pathways.With its high specificity and reliability, the COL19A1 Polyclonal Antibody is a valuable tool for researchers looking to explore the intricate functions of COL19A1 in various biological contexts. By enabling accurate detection and analysis of COL19A1 expression, this antibody opens up new possibilities for investigating the role of this protein in health and disease, paving the way for innovative research discoveries and potential therapeutic strategies.
Antibody Name:
COL19A1 Antibody
Antibody SKU:
PACO03453
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human COL19A1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
COL19A1: May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 6q12-q13Cellular Component: endoplasmic reticulum lumen; extracellular regionBiological Process: collagen catabolic process; skeletal development
UniProt Protein Details:
NCBI Summary:
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]
