COL11A2 Rabbit Polyclonal Antibody (CAB10473)
- SKU:
- CAB10473
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | COL11A2 Rabbit Polyclonal Antibody |
SKU: | CAB10473 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2). |
Sequence: | IVPG VQAA YESC EQKE LECE GGQR ERPQ NQQP HRAQ RSPQ QQPS RLHR PQNQ EPQS QPTE SLYY DYEP PYYD VMTT GTTP DYQD PTPG EEEE ILES SLLP PLEE EQTD LQVP PTAD RFQA EEYG EGGT DPPE GPYD YTYG YGDD YREE TELG PALS AETA HSGA AAHG PRG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HKE5; PARP; STL3; FBCG2; DFNA13; DFNB53; OSMEDA; OSMEDB; COL11A2 |
Positive Sample: | A375,HepG2,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 172kDa |
Observed MW: | 150kDa |
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
Purification Method: | Affinity purification |
Gene ID: | 1302 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |