Coilin Rabbit Monoclonal Antibody (CAB3483)
- SKU:
- CAB3483
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Coilin Rabbit Monoclonal Antibody |
SKU: | CAB3483 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Coilin (P38432). |
Sequence: | MAAS ETVR LRLQ FDYP PPAT PHCT AFWL LVDL NRCR VVTD LISL IRQR FGFS SGAF LGLY LEGG LLPP AESA RLVR DNDC LRVK LEER GVAE NSVV ISNG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CLN80; p80-coilin; Coilin |
Positive Sample: | HeLa,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cajal body, Nucleus. |
Calculated MW: | 63kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
Purification Method: | Affinity purification |
Gene ID: | 8161 |
Clone Number: | ARC0785 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |