The COG6 Polyclonal Antibody (CAB10319) is a powerful tool for researchers studying COG6, a protein involved in intracellular vesicle trafficking and protein glycosylation processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting COG6 in human samples, making it suitable for experiments such as Western blot analysis.COG6 is a subunit of the conserved oligomeric golgi (COG) complex, which plays a crucial role in maintaining the structure and function of the Golgi apparatus. Dysregulation of COG6 has been linked to various human diseases, including congenital disorders of glycosylation and neurological disorders.
Therefore, elucidating the function and regulation of COG6 is essential for understanding the underlying mechanisms of these conditions.By utilizing the COG6 Polyclonal Antibody, researchers can explore the intricate pathways in which COG6 is involved, paving the way for potential therapeutic interventions targeting COG6-related diseases. Its reliable performance and broad applicability make it a valuable asset for studies in cell biology, molecular biology, and biomedicine.
Product Name:
COG6 Rabbit Polyclonal Antibody
SKU:
CAB10319
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 508-657 of human COG6 (NP_065802.1).
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
57511
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using COG6 antibody (CAB10319) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.