The COG3 Polyclonal Antibody (CAB17785) is a valuable tool for researchers studying the COG3 protein, a key component of the conserved oligomeric Golgi (COG) complex involved in intracellular transport and protein glycosylation. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications.COG3 plays a critical role in maintaining the structure and function of the Golgi apparatus, making it essential for proper cellular trafficking and secretion.
Dysregulation of COG3 has been implicated in various diseases, including congenital disorders of glycosylation and neurodevelopmental disorders.By using the COG3 Polyclonal Antibody, researchers can accurately detect and analyze the expression levels of COG3 in different cell types, shedding light on its role in various cellular processes. This antibody is a valuable tool for studies in cell biology, molecular biology, and disease mechanisms involving protein glycosylation and intracellular trafficking.
Product Name:
COG3 Rabbit Polyclonal Antibody
SKU:
CAB17785
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human COG3 (NP_113619.2).
cis-Golgi network, cytosol, Golgi apparatus, Golgi transport complex, plasma membrane
Calculated MW:
94kDa
Observed MW:
94kDa
This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.
Purification Method:
Affinity purification
Gene ID:
83548
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using COG3 Rabbit pAb (CAB17785) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
