The COG2 Polyclonal Antibody (CAB6251) is a vital tool for researchers studying COG2, a protein involved in Golgi structure and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting COG2 in human samples, making it suitable for Western blot applications. By binding to the COG2 protein, this antibody enables accurate detection and analysis across a variety of cell types, making it an ideal choice for research in cell biology, molecular biology, and neuroscience.COG2 is a crucial component of the conserved oligomeric Golgi complex, playing a key role in maintaining the structure and function of the Golgi apparatus.
Dysregulation of COG2 has been linked to impairments in protein trafficking and secretion, impacting cellular processes such as glycosylation and vesicular transport. Research into COG2 is important for understanding fundamental cellular mechanisms and their implications for human health, including potential insights into genetic disorders and neurodegenerative diseases.By using the COG2 Polyclonal Antibody, researchers can delve deeper into the functions and dysfunctions of COG2, paving the way for new discoveries and therapeutic interventions in fields such as cell biology, neurobiology, and genetic disorders.
Product Name:
COG2 Rabbit Polyclonal Antibody
SKU:
CAB6251
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human COG2 (NP_031383.1).
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
22796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using COG2 Rabbit pAb (CAB6251) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 80s.
