The COG1 Polyclonal Antibody (CAB17594) is a valuable tool for researchers studying COG1, a protein involved in the maintenance of Golgi morphology and vesicular trafficking pathways. This antibody, produced in rabbits, is highly specific for detecting COG1 in human samples and has been validated for use in Western blot applications. By binding to the COG1 protein, this antibody enables researchers to study its localization and function in various cell types, making it an essential reagent for studies in cell biology and molecular biology.COG1 is a crucial component of the conserved oligomeric Golgi (COG) complex, which is responsible for mediating retrograde vesicular transport between Golgi compartments.
Dysregulation of COG1 has been implicated in various human diseases, including congenital disorders of glycosylation and neurological disorders. By investigating the role of COG1 using this antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially identify therapeutic targets for intervention. Discover the potential of COG1 research with the reliable and sensitive COG1 Polyclonal Antibody.
Product Name:
COG1 Rabbit Polyclonal Antibody
SKU:
CAB17594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 835-935 of human COG1 (NP_061184.1).
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
Purification Method:
Affinity purification
Gene ID:
9382
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 22Rv1 cells, using COG1 Rabbit pAb (CAB17594) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
