CFL2 Rabbit Polyclonal Antibody (CAB8009)
- SKU:
- CAB8009
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CFL2 Rabbit Polyclonal Antibody |
SKU: | CAB8009 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CFL2 (NP_068733.1). |
Sequence: | MASG VTVN DEVI KVFN DMKV RKSS TQEE IKKR KKAV LFCL SDDK RQII VEEA KQIL VGDI GDTV EDPY TSFV KLLP LNDC RYAL YDAT YETK ESKK EDLV FIFW APES APLK SKMI YASS KDAI KKKF TGIK HEWQ VNGL DDIK DRST LGEK LGGN VVVS LEGK PL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | NEM7; CFL2 |
Positive Sample: | A-549,HeLa,Raji,NCI-H460,Mouse heart,Mouse skeletal muscle,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus matrix, cytoskeleton. |
Calculated MW: | 19kDa |
Observed MW: | 18kDa |
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1073 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |