The Cocaine Esterase Polyclonal Antibody (CAB1514) is a valuable tool for research involving the enzyme cocaine esterase, which plays a critical role in the metabolism and inactivation of cocaine in the body. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of research applications including Western blotting.Cocaine esterase is a key enzyme involved in the breakdown of cocaine into inactive metabolites, ultimately reducing the drug's psychoactive effects. Understanding the mechanisms and regulation of cocaine esterase activity is crucial for developing treatments for drug addiction and overdose.
The CAB1514 antibody binds specifically to cocaine esterase, allowing for the detection and analysis of this enzyme in various biological samples.Research into cocaine esterase holds promise for the development of novel therapeutics for cocaine addiction and overdose treatment. By using the CAB1514 antibody, researchers can investigate the role of cocaine esterase in drug metabolism and explore potential strategies for enhancing its activity as a therapeutic approach. This antibody is a valuable tool for studies in pharmacology, toxicology, and addiction research.
Product Name:
CES2 Rabbit Polyclonal Antibody
SKU:
CAB1514
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 310-410 of human CES2 (NP_003860.3).
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CES2 antibody (CAB1514) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
