The CNTNAP3B Polyclonal Antibody (PAC064215) is a valuable tool for research involving CNTNAP3B, a cell adhesion molecule known for its role in neural development and synaptic function. This antibody, raised in rabbits, exhibits high specificity and sensitivity for human samples, making it a reliable choice for experiments in various cell types.CNTNAP3B, also referred to as Caspr3, is a member of the neurexin superfamily and is essential for proper assembly of nodes of Ranvier in myelinated axons. Dysfunction of CNTNAP3B has been associated with neurological disorders such as schizophrenia and epilepsy, making it a target of interest for researchers studying brain development and function.
By using the CNTNAP3B Polyclonal Antibody, researchers can detect and analyze the expression of CNTNAP3B in biological samples, furthering our understanding of its role in neural processes. This antibody is validated for use in Western blot applications, providing reliable results for studies in neuroscience and neurology. Explore the functions and implications of CNTNAP3B with this research-grade antibody.
Antibody Name:
CNTNAP3B Antibody (PACO64215)
Antibody SKU:
PACO64215
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:200-1:500, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Contactin-associated protein-like 3B protein (26-256AA)
IHC image of PACO64215 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Immunofluorescence staining of A549 cells with PACO64215 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
CNTNAP3B: Belongs to the neurexin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesion; Membrane protein, integralChromosomal Location of Human Ortholog: 9p11.2Cellular Component: integral to membraneBiological Process: cell adhesion
