CNTFR Rabbit Polyclonal Antibody (CAB2700)
- SKU:
- CAB2700
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CNTFR Rabbit Polyclonal Antibody |
SKU: | CAB2700 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1). |
Sequence: | FHRD SWHL RHQV LLHV GLPP REPV LSCR SNTY PKGF YCSW HLPT PTYI PNTF NVTV LHGS KIMV CEKD PALK NRCH IRYM HLFS TIKY KVSI SVSN ALGH NATA ITFD EFTI VKPD PPEN VVAR PVPS NPRR LEVT WQTP STWP DPES FPLK FFLR YRPL ILDQ WQHV ELSD GTAH TITD AYAG KEYI IQVA AKDN EIGT WSDW SVAA HATP WTEE PRHL TTEA QAAE TTTS TTSS LAPP PTTK ICDP GELG S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:400 - 1:2000 |
Synonyms: | CNTFR |
Positive Sample: | U-87MG,HeLa,Mouse brain,Mouse heart,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1271 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |