The CNR2 Polyclonal Antibody (CAB1762) is specifically designed for research involving the cannabinoid receptor 2 (CNR2), a key player in the endocannabinoid system. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in Western blot and immunohistochemistry applications. It binds to the CNR2 protein, allowing for the detection and analysis of CNR2 expression in various tissue types.CNR2, also known as CB2, is involved in regulating immune responses, inflammation, and pain perception. Its role in modulating these processes makes it a promising target for research in a variety of fields, including immunology, neurology, and pain management.
Understanding the function of CNR2 can provide insights into potential therapeutic strategies for conditions such as chronic pain, inflammatory disorders, and neurological diseases.Overall, the CNR2 Polyclonal Antibody (CAB1762) is a valuable tool for researchers studying the role of CNR2 in health and disease. Its high reactivity and specificity make it ideal for investigating the expression and function of CNR2 in various experimental settings.
Product Name:
CNR2 Rabbit Polyclonal Antibody
SKU:
CAB1762
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CNR2 (NP_001832.1).
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Purification Method:
Affinity purification
Gene ID:
1269
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CNR2 Rabbit pAb (CAB1762) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
