CNOT7 Rabbit Polyclonal Antibody (CAB8959)
- SKU:
- CAB8959
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CNOT7 Rabbit Polyclonal Antibody |
SKU: | CAB8959 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2). |
Sequence: | PGTS TWQF NFKF NLTE DMYA QDSI ELLT TSGI QFKK HEEE GIET QYFA ELLM TSGV VLCE GVKW LSFH SGY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CAF1; CAF-1; Caf1a; hCAF-1; CNOT7 |
Positive Sample: | 22Rv1,U-87MG,HT-29,Raji,HeLa,Mouse lung,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, P-body. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
Purification Method: | Affinity purification |
Gene ID: | 29883 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |