The CNOT3 Polyclonal Antibody (PACO08493) is a valuable tool for researchers studying CNOT3, a key protein involved in gene regulation and mRNA degradation processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in Western blotting applications. By binding to the CNOT3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it essential for studies in molecular biology and cancer research.CNOT3, a component of the CCR4-NOT complex, plays a crucial role in controlling gene expression by regulating mRNA decay and transcriptional elongation. Its involvement in these processes makes it a target of interest for researchers investigating cellular proliferation, differentiation, and development.
Understanding the function of CNOT3 is essential for deciphering its role in various biological pathways and diseases, including cancer and neurological disorders.In conclusion, the CNOT3 Polyclonal Antibody (PACO08493) is a reliable tool for investigating the function and expression of CNOT3 in cellular processes. Its validation for Western blotting and high reactivity with human samples make it an essential resource for researchers seeking to unravel the intricate mechanisms of gene regulation and mRNA degradation mediated by CNOT3.
NOT3: The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the CNOT2/3/5 family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 19q13.4Cellular Component: nucleus; cytosol; CCR4-NOT complexMolecular Function: protein bindingBiological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA-mediated gene silencing; gene expression; trophectodermal cell differentiation; mRNA catabolic process, deadenylation-dependent decay
