CNOT1 Rabbit Polyclonal Antibody (CAB5969)
- SKU:
- CAB5969
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CNOT1 Rabbit Polyclonal Antibody |
SKU: | CAB5969 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2137-2376 of human CNOT1 (NP_057368.3). |
Sequence: | PRNM RLPD PFTP NLKV DMLS EINI APRI LTNF TGVM PPQF KKDL DSYL KTRS PVTF LSDL RSNL QVSN EPGN RYNL QLIN ALVL YVGT QAIA HIHN KGST PSMS TITH SAHM DIFQ NLAV DLDT EGRY LFLN AIAN QLRY PNSH THYF SCTM LYLF AEAN TEAI QEQI TRVL LERL IVNR PHPW GLLI TFIE LIKN PAFK FWNH EFVH CAPE IEKL FQSV AQCC MGQK QAQQ VMEG TGAS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | NOT1; CDC39; HPE12; NOT1H; VIBOS; AD-005; CNOT1 |
Positive Sample: | U-87MG,293T,LO2,A-549,HeLa,mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, P-body. |
Calculated MW: | 267kDa |
Observed MW: | 267kDa |
Enables armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Contributes to poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Located in P-body and cytosol. Part of CCR4-NOT complex. Implicated in holoprosencephaly.
Purification Method: | Affinity purification |
Gene ID: | 23019 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |