The CNNM4 Polyclonal Antibody (CAB17130) is a valuable tool for researchers studying CNNM4, a protein involved in magnesium homeostasis and cell proliferation. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blotting and immunohistochemistry applications.CNNM4 plays a crucial role in maintaining cellular magnesium levels, which are essential for various physiological processes such as DNA synthesis and energy metabolism. Dysregulation of CNNM4 has been linked to diseases like hypomagnesemia and epilepsy, making it a target of interest for therapeutic interventions.
By using the CNNM4 Polyclonal Antibody, researchers can investigate the expression and localization of CNNM4 in different cell types and tissues, providing insights into its function and potential implications in disease pathology. This antibody serves as a reliable tool for furthering our understanding of magnesium homeostasis and its impact on human health.
Product Name:
CNNM4 Rabbit Polyclonal Antibody
SKU:
CAB17130
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-775 of human CNNM4 (NP_064569.3).
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta.
Purification Method:
Affinity purification
Gene ID:
26504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CNNM4 antibody (CAB17130) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
