The CNN1 Polyclonal Antibody (CAB16638) is a valuable tool for researchers studying CNN1, a protein involved in smooth muscle contraction and important for various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CNN1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in muscle biology and cardiovascular research.
CNN1, also known as calponin 1, is crucial for regulating smooth muscle contraction and cell motility. Dysregulation of CNN1 has been implicated in cardiovascular diseases such as hypertension and atherosclerosis, making it a promising target for therapeutic interventions. Understanding the role of CNN1 in muscle function and disease pathology is essential for developing new treatment strategies and advancing our knowledge of smooth muscle biology.
Product Name:
Calponin Rabbit Polyclonal Antibody
SKU:
CAB16638
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-297 of human Calponin (NP_001290.2).
Mouse large intestine,Mouse stomach,Rat lung,Rat stomach,Rat uterus
Conjugate:
Unconjugated
Cellular Localization:
cytoskeleton, focal adhesion
Calculated MW:
33kDa
Observed MW:
33kDa
Predicted to enable actin binding activity. Involved in negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
1264
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Calponin antibody (CAB16638) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
