The CNKSR3 Polyclonal Antibody (PAC050690) is a valuable tool for researchers studying CNKSR3, a protein involved in cell signaling pathways and regulation of cellular processes. This antibody, raised in rabbits, is highly specific for CNKSR3 in human samples and is validated for use in various applications, including Western blotting. By binding to CNKSR3, this antibody allows for the detection and analysis of the protein in different cell types, making it an ideal choice for studies in molecular biology and cancer research.CNKSR3, also known as connector enhancer of kinase suppressor of Ras 3, plays a crucial role in signaling cascades that control cell growth, differentiation, and survival.
Its involvement in these processes makes CNKSR3 a potential target for therapeutic interventions in diseases such as cancer and neurological disorders. Understanding the functions of CNKSR3 can provide insights into the underlying mechanisms of disease and help in the development of targeted treatments.Overall, the CNKSR3 Polyclonal Antibody is a valuable reagent for researchers interested in studying the biological functions of CNKSR3 and its potential implications in disease pathogenesis. Its high specificity and reliability make it a trusted tool for investigating the role of CNKSR3 in various cellular processes and disease states.
Immunofluorescent analysis of HepG2 cells using PACO50690 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Western Blot. Positive WB detected in: Mouse spleen tissue. All lanes: CNKSR3 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 62, 101, 93 kDa. Observed band size: 62 kDa.
Background:
Probably involved in transepithelial sodium transport. Regulates aldosterone-induced and ENaC-mediated sodium transport possibly through regulation of the ERK pathway (By similarity).
Synonyms:
Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein), CNKSR3, MAGI1
UniProt Protein Function:
CNKSR3: Probably involved in transepithelial sodium transport. Regulates aldosterone-induced and ENaC-mediated sodium transport possibly through regulation of the ERK pathway. Belongs to the CNKSR family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 6q25.2Cellular Component: membrane; cytoplasmBiological Process: negative regulation of peptidyl-serine phosphorylation
