The CNKSR2 Polyclonal Antibody (CAB14578) is a valuable tool for researchers studying CNKSR2, a scaffold protein involved in various signaling pathways. This antibody, produced in rabbits, shows high specificity and sensitivity towards CNKSR2 in human samples, making it suitable for Western blot applications. By targeting the CNKSR2 protein, researchers can accurately detect and investigate its role in cell signaling processes in different cell types, opening up possibilities for research in areas such as cell biology and cancer biology.
CNKSR2, also known as connector enhancer of KSR 2, is a key player in mediating protein-protein interactions and regulating signal transduction pathways involved in cell growth and differentiation. Its involvement in various cellular processes makes it an attractive target for studying disease mechanisms and developing potential therapeutic interventions. The CNKSR2 Polyclonal Antibody provides researchers with a reliable tool to delve deeper into the functions of CNKSR2 and its implications in physiological and pathological conditions.
Product Name:
CNKSR2 Rabbit Polyclonal Antibody
SKU:
CAB14578
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2).
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22866
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CNKSR2 Rabbit pAb (CAB14578) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.