The CNIH3 Polyclonal Antibody (PACO08483) is a valuable tool for researchers studying CNIH3, a protein involved in ion channel regulation and synaptic plasticity. This antibody, generated in rabbits, shows high reactivity towards human samples and has been validated for use in Western blot applications. By targeting the CNIH3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in neurobiology and neuroscience research.CNIH3 plays a key role in modulating the activity of ion channels in the brain, influencing synaptic transmission and plasticity. Its involvement in neuronal signaling makes it a promising target for investigating neurological disorders such as epilepsy, Alzheimer's disease, and schizophrenia.
Understanding the function of CNIH3 can provide insights into the mechanisms underlying these conditions, potentially leading to the development of new therapeutic strategies.Overall, the CNIH3 Polyclonal Antibody (PACO08483) is a reliable tool for researchers interested in exploring the role of CNIH3 in neuronal function and neurological disorders. Its specificity and sensitivity make it a valuable asset for advancing our understanding of ion channel regulation in the brain.
CNIH3: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Belongs to the cornichon family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1q42.12Cellular Component: dendritic shaft; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; postsynaptic membraneBiological Process: COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport
