| UniProt Protein Function: | Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. |
| UniProt Protein Details: | |
| NCBI Summary: | In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
| UniProt Code: | Q14028 |
| NCBI GenInfo Identifier: | 208431781 |
| NCBI Gene ID: | 1258 |
| NCBI Accession: | NP_001129111.1 |
| UniProt Secondary Accession: | Q14028,O43636, Q13059, Q14029, Q9UMG2, H3BN09 |
| UniProt Related Accession: | Q14028 |
| Molecular Weight: | 139,179 Da |
| NCBI Full Name: | cyclic nucleotide-gated cation channel beta-1 isoform b |
| NCBI Synonym Full Names: | cyclic nucleotide gated channel beta 1 |
| NCBI Official Symbol: | CNGB1Â Â |
| NCBI Official Synonym Symbols: | CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta  |
| NCBI Protein Information: | cyclic nucleotide-gated cation channel beta-1 |
| UniProt Protein Name: | Cyclic nucleotide-gated cation channel beta-1 |
| UniProt Synonym Protein Names: | Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-1; CNG channel beta-1; Glutamic acid-rich protein; GARP |
| Protein Family: | Cyclic nucleotide-gated cation channel |
| UniProt Gene Name: | CNGB1Â Â |
| UniProt Entry Name: | |
