CNGB1 Antibody (PACO06363)
- SKU:
- PACO06363
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
CNGB1 Antibody (PACO06363)
The Cngb1 Antibody (PACO06363) is a highly specific polyclonal antibody designed for research purposes involving the CNGA1 protein. CNGA1 is a key component of cyclic nucleotide-gated ion channels, which play important roles in sensory transduction in the retina and olfactory epithelium.This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blot and immunohistochemistry. By specifically binding to the CNGA1 protein, researchers can effectively detect and analyze its expression in various cell types and tissues.
The Cngb1 Antibody holds great potential for studies in neuroscience, vision science, and molecular biology, providing valuable insights into the function and regulation of cyclic nucleotide-gated ion channels. Its application in research may contribute to the development of novel therapeutic approaches for conditions related to sensory perception and signal transduction.
| Antibody Name: | CNGB1 Antibody (PACO06363) |
| Antibody SKU: | PACO06363 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human CNG-1 β . |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of NIH-3T3 cells using CNG-1 beta Polyclonal Antibody. |
 | Western Blot analysis of 3T3 cells using CNG-1 beta Polyclonal Antibody. |
| Synonyms: | CNGB1; CNCG2; CNCG3L; CNCG4; RCNC2; Cyclic nucleotide-gated cation channel β-1; Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel γ; Cyclic nucleotide-gated cation channel mo |
| UniProt Protein Function: | Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. |
| UniProt Protein Details: | |
| NCBI Summary: | In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
| UniProt Code: | Q14028 |
| NCBI GenInfo Identifier: | 208431781 |
| NCBI Gene ID: | 1258 |
| NCBI Accession: | NP_001129111.1 |
| UniProt Secondary Accession: | Q14028,O43636, Q13059, Q14029, Q9UMG2, H3BN09 |
| UniProt Related Accession: | Q14028 |
| Molecular Weight: | 139,179 Da |
| NCBI Full Name: | cyclic nucleotide-gated cation channel beta-1 isoform b |
| NCBI Synonym Full Names: | cyclic nucleotide gated channel beta 1 |
| NCBI Official Symbol: | CNGB1Â Â |
| NCBI Official Synonym Symbols: | CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta  |
| NCBI Protein Information: | cyclic nucleotide-gated cation channel beta-1 |
| UniProt Protein Name: | Cyclic nucleotide-gated cation channel beta-1 |
| UniProt Synonym Protein Names: | Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-1; CNG channel beta-1; Glutamic acid-rich protein; GARP |
| Protein Family: | Cyclic nucleotide-gated cation channel |
| UniProt Gene Name: | CNGB1Â Â |
| UniProt Entry Name: |
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